Isotopics – November 2022 | Edition 13

Welcome to the [carbon] 13^th edition of IsoTopics! Did you know triskaidekaphobia is the fear of the number 13? While some people may shy away from this number, CIL embraces it, as we are the world’s leading producer of ¹³C stable isotopes. There are many benefits of using ¹³C standards so we have been incorporating these into some of our newest mixes. Take our TCA cycle mix, for instance, which encompasses 13 components, all ¹³C labeled! If you are interested in seeing what others are doing with our ¹³C-labeled products, make sure to read the articles that have been highlighted in this ¹³C edition of IsoTopics. If you’re not afraid, that is.

Cardiac Myosin Filaments are Maintained by Stochastic Protein Replacement

Wood, N.B.; Kelly, C.M.; O’Leary, T.S.; et al.

An Optimized MRM-Based Workflow of the L-Arginine/Nitric Oxide Pathway Metabolites Revealed Disease- and Sex-Related Differences in the Cardiovascular Field

Porro, B.; Eligini, S.; Conte, E.; et al.

Continuous Oral Stable Isotope Ingestion to Measure Whole-Body Protein Turnover

Hirsch, K.R.; Church, D.D.; Wolfe, R.R.; et al.

The Metabolism of Human Soluble Amyloid Precursor Protein Isoforms Is Quantifiable by a Stable Isotope Labeling-Tandem Mass Spectrometry Method

Zakaria, J.A.D.; Bateman, R.J.; Lysakowska, M.; et al.

TurnoveR: A Skyline External Tool for Analysis of Protein Turnover in Metabolic Labeling Studies

Basisty, N.; Shulman, N.; Wehrfritz, C.; et al.

Isotope Tracing in Health and Disease

Dong, W.; Rawat, E.S.; Stephanopoulos, G.; et al.