Mass Spectrometry

Amplatz, B.; et al. 2017. Bile acid preparation and comprehensive analysis by high performance liquid chromatography-high-resolution mass spectrometry. Clin Chim Act, 464, 85-92. PMID: 27838249

Wegner, K.; et al. 2017. Rapid analysis of bile acids in different biological matrices using LC-ESI-MS/MS for the investigation of bile acid transformation by mammalian gut bacteria. Anal Bioanal Chem, 409(5), 1231-1245. PMID: 27822648

Sarafian, M.H.; et al. 2015. Bile acid profiling and quantification in biofluids using ultra-performance liquid chromatography tandem mass spectrometry. Anal Chem, 87(19), 9662-9670. PMID: 26327313

Han, J.; et al. 2015. Metabolic profiling of bile acids in human and mouse blood by LC-MS/MS in combination with phosopholipid-depletion solid-phase extraction. Anal Chem, 87(2), 1127-1136. PMID: 25496250

Gertsman, I.; et al. 2014. Validation of a dual LC-HRMS platform for clinical metabolic diagnosis in serum, bridging quantitative analysis and untargeted metabolomics. Metabolomics, 10(2), 312-323. PMID: 25411574

Suzuki, Y.; et al. 2013. Simple and rapid quantitation of 21 bile acids in rat serum and liver by UPLC-MS-MS: effect of high fat diet on glycine conjugates of rat bile acids. Nagoya J Med Sci, 75(1-2), 57-71. PMID: 23544269

Schrire, B.D.; et al. 2002. Indigofera mauritanica internal transcribed spacer 1, partial sequence; 5.8S ribosomal RNA gene, complete sequence; and internal transcribed spacer 2, partial sequence. Adv Legume Syst, 10. NCBI: AF521794.1

Biomolecular NMR 

Harbers, M. 2014. Wheat germ systems for cell-free protein expression. FEBS Lett, 588(17), 2762-2773. PMID: 24931374

Sinnige, T.; Daniels, M.; Baldus, M.; et al. 2014. Proton Clouds to Measure Long-Range Contacts between Nonexchangeable Side Chain Protons in Solid-State NMR. J Am Chem Soc, 136(12), 4452-4455. PMID: 24467345

Weingarth, M.; Baldus., M. 2013.  Solid-State NMR-Based Approaches for Supramolecular Structure Elucidation. Acc Chem Res, 46(9), 2037-2046. PMID: 23586937

Loquet, A.; Habenstein, B.; Lange, A. 2013. Structural Investigations of Molecular Machines by Solid-State NMR. Acc Chem Res, 46(9), 2013-2079. PMID: 23496894

Verardi, R.; Traaseth, N.J.; Masterson, L. R.; et al. 2012. Isotope Labeling for Solution and Solid-State NMR Spectroscopy of Membrane Proteins. Adv Ex Med Bio, 992, 35-62. PMID: 23076578

Huber, M.; Hiller, S.; Schanda, P.; et al. 2012. A Proton-Detected 4D Solid-State NMR Experiment for Protein Structure Determination. Chem Phys Chem, 12(5), 915-918. PMID: 21442705

Park, S.H.; Das, B.B.; Casagrande. F.; et al. 2012. Structure of the chemokine receptor CXCR1 in phospholipid bilayers. Nature, 491(7426), 779-783. PMID: 23086146

Takeuchi, K.; Frueh, D.P.; Sun, Z.Y.; et al. 2010. HNCA-TOCSY-CANH experiments with alternate ¹³C-¹²C labeling: a set of 3D experiment with unique supra-sequential information for mainchain resonance assignment. J Biomol NMR, 49(1), 17-26. PMID: 21110064

Thakur, C.S.; Sama, J.N.; Jackson, M.E.; et al. 2010. Selective ¹³C labeling of nucleotides for large RNA NMR spectroscopy using an E. coli strain disabled in the TCA cycle. J Biomol NMR, 48(4), 179-192. PMID: 21057854

Wagner, G.; Lu, K.; Miyazaki, Y.; et al. 2010. A topical issue: production and labeling of biological macromolecules for NMR investigations J Biomol NMR, 46(1), 113-125. PMID: 19924385

Krishnarjuna, B.; Jaiupuria, G.; Thakur, A.D.; et al. 2010. Amino acid selective unlabeling for sequence specific resonance assignments in proteins. J Biomol NMR, 49(1), 38-51. PMID: 21153044

Zhu, J.; Ye, E.; Terskikh, V.; et al. 2010. Solid-state ¹⁷O NMR spectroscopy of large protein-ligand complexes. Angew Chem Int Ed, 49(45), 8399-8402. PMID: 20672261

Takahashi, H.; Shimada, I. 2010. Production of isotopically labeled heterologous proteins in non-E. coli prokaryotic and eukaryotic cells. J Biomol NMR, 46(1), 3-10. PMID: 19787297

Filipp, F.V.; Sinha, N.; Jairam, L.; et al. 2009. Labeling strategies for ¹³C-detected aligned-sample solid-state NMR of proteins. J Magn Reson, 201(2), 121-130. PMID: 19781966

Ayala, I.; Sounier, R.; Use, N.; et al. 2009. An efficient protocol for the complete incorporation of methyl-protonated alanine in perdeuterated protein. J Biomol NMR, 43(2), 111-119. PMID: 19115043

Wylie, B.J. 2009. Protein Structure Refinement Using ¹³Cα Chemical Shift Tensors. J Am Chem Soc, 131(3), 985-992. PMID: 19123862

Tong, K.I.; Yamamoto, M.; Tanaka, T. 2008. A simple method for amino acid selective isotope labeling of recombinant proteins in E. coli. J Biomol NMR, 42(1), 59-67. PMID: 18762866

Hiller, S.; Garces, R.G.; Malia, T.J.; et al. 2008. Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Science, 321(5893), 1206-1210. PMID: 18755977

Zhou, Y.; Cierpicki, T.; Jimenez, R.H.; et al. 2008. NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Mol Cell, 31(6), 896-908. PMID: 18922471

Takeuchi, K.; Ng, E.; Malia, T.J.; et al. 2007. 1-¹³C amino acid selective labeling in a ²H¹⁵N background for NMR studies of large proteins. J Biomol NMR, 38(1), 89-98. PMID: 17390105

Isaacson, R.L.; Simpson, P.J.; Liu, M.; et al. 2007. A new labeling method for methyl transverse relaxation-optimized spectroscopy NMR spectra of alanine residues. J Am Chem Soc, 129(50), 15428-15429. PMID: 18041839

Kainosho, M.; Torizawa, T.; Iwashita, Y.; et al. 2006. Optimal isotope labeling for NMR protein structure determinations. Nature, 440(7080), 52-57. PMID: 16511487

Frueh, D.P.; Vosburg, D.A.; Walsh, C.T.; et al. 2006. Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins. J Am Chem Soc, 128(17), 5757-5763. PMID:16637644

Chen, C.Y.; Cheng, C.H.; Chen, Y.C.; et al. 2006. Preparation of amino-acid-type selective isotope labeling of protein expressed in Pichia pastoris. Proteins, 62(1), 279-287. PMID: 16283643

Davis, J.H.; Tonelli, M.; Scott, L.G.; et al. 2005. RNA Helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex. J Mol Biol, 351(2), 371-382. PMID: 16002091

Tugarinov, V.; Kay, L.E. 2005. Methyl groups as probes of structure and dynamics in NMR studies of high-molecular-weight proteins. Chembiochem, 6(9), 1567-1577. PMID: 16075427

Tyler, R.C.; Sreenath, H.K.; Singh, S.; et al. 2005. Auto-induction medium for the production of [U-¹⁵N]- and [U-¹³C, U-¹⁵N]-labeled proteins for NMR screening and structure determination. Protein Expr Purif, 40(2), 268-278. PMID: 15766868

Torizawa, T.; Shimizu, M.; Taoka, M.; et al. 2004. Efficient production of isotopically labeled proteins by cell-free synthesis: A practical protocol. J Biomol NMR, 30(3), 311-325. PMID: 15754057

Pickford, A.R.; O‘Leary, J.M. 2004. Isotopic labeling of recombinant proteins from the methylotrophic yeast Pichia pastoris. Methods Mol Biol, 278, 17-33. PMID: 15317988

Rodriguez-Mias, R.; Pellecchia, M. 2003. Use of Selective Trp Side Chain Labeling to Characterize Protein-Protein and Protein-Ligand Interactions by NMR Spectroscopy. J Am Chem Soc, 125(10), 2892-2893. PMID: 12617653

Castellani, F.; van Rossum, B.; Diehl, A.; et al. 2002. Structure of a protein determined by solid-state magic-angle-spinning NMR spectroscopy. Nature, 420(6911), 98-102. PMID: 12422222

Hwang, P.M.; Choy, W.Y.; Lo, E.I.; et al. 2002. Solution structure and dynamics of the outer membrane enzyme PagP by NMR. Proc Natl Acad Sci USA, 99(21), 13560-13565. PMID: 12357033

Rodriguez, E.; Krishna, N.R. 2001. An economical method for ¹⁵N / ¹³C isotopic labeling of proteins expressed in Pichia pastoris. J Biochem, 130(1), 19-22. PMID: 11432775

Cowburn, D. and Muir, T.W. 2001. Segmental isotopic labeling for structural biological applications of NMR. Methods Mol Biol, 278, 47–56. PMID: 15317990

Atreya, H.S.; Chary, K.V.R. 2001. Selective unlabeling of amino acids in fractionally ¹³C-labeled proteins: An approach for stereospecific NMR assignments of CH₃ groups in Val and Leu residues. J Biomol NMR, 19(3), 267-272. PMID: 11330814

Morgan, W.D.; Kragt, A.; Feeney, J. 2000. Expression of deuterium-isotope-labeled protein in the yeast Pichia pastoris for NMR studies. J Biomol NMR, 17(4), 337-347. PMID: 11014598

Goto, N.K.; Gardner, K.H.; Mueller, G.A.; et al. 1999. A robust and cost-effective method for the production of Val, Leu, Ile (δ1) methyl-protonated ¹⁵N-, ¹³C-, ²H-labeled proteins. J Biomol NMR, 13(4), 369-374. PMID: 10383198

Wood, M.J.; Komives, E.A. 1999. Production of large quantities of isotopically labeled protein in Pichia pastoris by fermentation. J Biomol NMR, 13(2), 149-159. PMID: 10070756

Massou, S.; Puech, V.; Talmont, F.; et al. 1999. Heterologous expression of a deuterated membrane-integrated receptor and partial deuteration in methylotrophic yeasts. J Biomol NMR, 14(3), 231-239. PMID: 10481275

Hong, M. 1999. Determination of multiple phi-torsion angles in proteins by selective and extensive ¹³C labeling and two-dimensional solid-state NMR. J Magn Reson, 139(2), 389-401. PMID: 10423377

Gardner, K.H.; Kay, L.E. 1997. Production and Incorporation of ¹⁵N, ¹³C, ²H (¹H δ1 methyl) Isoleucine into Proteins for Multidimensional NMR Studies. J Am Chem Soc, 119(32), 7599-7600. JACS DOI: 10.1021/ja9706514

Batey, R.T. 1996. Improved large-scale culture of Methylophilus methylotrophus for ¹³C / ¹⁵N labeling and random fractional deuteration of ribonucleotides. Nucleic Acids Res, 24(23), 4836-4837. PMID: 8972874

Vuister, G.W.; Kim, S.J.; Wu, C.; et al. 1994. 2D and 3D NMR study of phenylalanine residues in proteins by reverse isotopic labeling. J Am Chem Soc, 116(20), 9206-9210 JACS DOI:10.1021/ja00099a041

Ikura, M.; Kay, L.E.; Bax, A. 1990. A novel approach for sequential assignment of ¹H, ¹³C, and ¹⁵N spectra of larger proteins: heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to Calmodulin. Biochemistry, 29(19), 4659-4667. PMID: 2372549

Metabolic Research

Geary, B.; Magee, K.; Cash, P.; et al. 2016. Determining synthesis rates of individual proteins in zebrafish (Danio rerio) with low levels of a stable isotope labelled amino acid. Proteomics, 16(9), 1398-1406. PMID: 26929125

Sellers, K.; Fox, M.; Bousamra, M.; et al. 2015. Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation. J Clin Invest, 125(2), 687-698. PMID: 25607840

Buescher, J.; Antoniewicz, M.; Boros, L.; et al. 2015. A roadmap for interpreting 13C metabolite labeling patterns from cells. Curr Opin Biotechnol 34, 189-201. PMID: 25731751

Mayers, J.R., et al., 2014. Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development. Nat Med, 20(10), 1193-1208. PMID: 25261994

Lewis, C., et al. 2014. Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells. Mol Cell, 55(2), 253-263. PMID: 24882210

Fan, J.; Ye, J.; Kamphorst, J.; et al. 2014. Quantitative flux analysis reveals folate-dependent NADPH production. Nature, 510(7504), 298-302. PMID: 24805240

Marini, J.C., et al. 2012. Arginine and Ornithine Are the Main Precursors for Citrulline Synthesis in Mice. J Nutrition, 142(3), 572-580. PMID: 22323761

Proteomics 

Shwaiger, M.; Rampler, E.; Hermann, G.; et al. 2017. Anion-exchange chromatography coupled to high resolution mass spectrometry: a powerful tool for merging targeted and non-targeted metabolomics. Anal Chem, 89(14), 7667-7674. PMID: 28581703

Percy, A.J.; Byrns, S.; Pennington, S.R.; et al. 2016. Clinical translation of MS- based, quantitative plasma proteomics: status, challenges. Expert Rev Proteomics, 13(7), 673-684. PMID: 27341553 

Bao, X.R.; Ong, S.E.; Goldberger, O.; et al. 2016. Mitochondrial dysfunction remodels one-carbon metabolism in human cells. Elife, 16(5), e10575. PMID: 27307216 

McConnell, B.O.; Antoniewicz, M.R. 2016. Measuring the Composition and Stable-Isotope Labeling of Algal Biomass Carbohydrates via Gas Chromatography/Mass Spectrometry. Anal Chem, 88(9), 4624-4628. PMID: 27042946

Baughman, J.M.; Rose, C.M.; Koluman, G.; et al. 2016. NeuCode Proteomics Reveals Bap1 Regulation of Metabolism. Cell Rep,16(2), 583-595. PMID: 27373151

Geary, B.; Magee, K.; Cash, P.; et al. 2016. Determining synthesis rates of individual proteins in zebrafish (Danio rerio) with low levels of a stable isotope labelled amino acid. Proteomics, 16(9), 1398-1406. PMID: 26929125

Hecht, E.S.; McCord, J.P.; Muddiman, D.C. 2016. A Quantitative Glycomics and Proteomics Combined Purification Strategy. J Vis Exp, 8(109). PMID: 27023253

Baughman, JM; Rose, CM; Koluman, G. 2016. NeuCode Proteomics Revearls Bap1 Regulation of Metabolism. Cell Rep, 16(2), 583-595. PMID: 27373151 

Singh, S.A.; Andraski, A.B.; Pieper, B.; et al. 2016. Multiple apolipoprotein kinetics measured in human HDL by high-resolution/accurate mass parallel reaction monitoring. J Lipid Res, 57(4), 714-728. PMID: 26862155

Henderson, C.M.; Vaisar, T.; Hoofnagle, A.N. 2016. Isolating and Quantifying Plasma HDL Proteins by Sequential Density Gradient Ultracentrifugation and Targeted Proteomics. Methods Mol Biol, 1410, 105-20. PMID: 26867741

Zhang, A.; Uaesoontrachoon, K.; Shaughnessy, C.; et al. 2015. The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse. Toxicol Rep, 838-849. PMID: 26213685

Wang, D.; Krilich, J.; Baudys, J.; et al. 2015. Optimization of peptide substrates for botulinum neurotoxin E improves detection sensitivity in the Endopep-MS assay. Anal Biochem, 468, 15-21. PMID: 25232998 

Cox, T.R.; Schoof, E.M.; Gartland, A.; et al. 2015. Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism. Data Brief, 5, 621-625. PMID: 26649326

Hecht, E.S.; Scholl, E.H.; Walker, S.H.; et al. 2015. Relative Quantification and Higher-Order Modeling of the Plasma Glycan Cancer Burden Ratio in Ovarian Cancer Case-Control Samples. J Proteome Res, 14(10), 4394-4401. PMID: 26347193

Mohammed, Y.; Percy, A.J.; Chambers, A.G.; et al. 2015. Qualis-SIS: automated standard curve generation and quality assessment for multiplexed targeted quantitative proteomic experiments with labeled standards.J Proteome Res. 14(2), 1137-1146. PMID: 25546269

Percy, A.J.; Mohammed, Y.; Yang, J.; et al. 2015. A Standard kit for automated quantitative assessment of candidate protein biomakers in human plasma. Bioanalysis, 7(23), 2991-3004. PMID: 26626236

Murphy, J.P.; Everley, R.A.; Coloff, J.L.; et al. 2014. Combining amine metabolomics and quantitative proteomics of cancer cells using derivatization with isobaric tags. Anal Chem, 86(7), 3585-3593. PMID: 24611633

Hathout, Y.; Marathi, R.L.; Rayavarapu, S.; et al. 2014. Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients. Hum Mol Genet, 23(24), 6458-6469. PMID: 25027324 

Edfors, F.; Bostrom, T.; Forsstrom, B.; et al. 2014. Immunoproteomics using polyclonal antibodies and stable isotope-labeled affinity-purified recombinant proteins. Mol Cell Proteomics, 13(6), 1611-1624. PMID: 24722731

Bagert, J.D.; Xie, Y.J.; Sweredoski, M.J.; et al. 2014. Quantitative, time-resolved proteomic analysis by combining bioorthogonal noncanonical amino acid tagging and pulsed stable isotope labeling by amino acids in cell culture. Mol Cell Proteomics, 13(5), 1352-1358. PMID: 24563536

McShane, A.J.; Bajrami, B.; Ramos, A.A.; et al. 2014. Targeted proteomic quantitation of the absolute expression and turnover of cystic fibrosis transmembrane conductance regulator in the apical plasma membrane. J Proteome Res, 13(11), 4676-4685. PMID: 25227318

Percy, A.J.; Chambers, A.G.; Yang, J.; et al. 2014. Advances in multiplexed MRM-based protein biomarker quantitation toward clinical utility. Biochim Biophys Acta, 1844(5), 917-926. PMID: 23806606

Adhikari, J.; Fitzgerald, M.C. 2014. SILAC-Pulse Proteolysis: A Mass Spectrometry-Based Method for Discovery and Cross-Validation in Proteome-Wide Studies of Ligand Binding. J Am Soc Mass Spectrom, 25(12), 2073-2083. PMID: 25315461

Zhang, C.; Liu, Y.; Andrews, P.C. 2013. Quantification of histone modifications using ¹⁵N metabolic labeling. Methods, 61(3), 236-243. PMID: 23454290

Hessling, B.; Buttner, K.; Hecker, M.; et al. 2013. Global relative quantification with liquid chromatography-matrix-assisted laser desorption ionization time-of-flight (LC-Maldi-TOF)-cross-validation with LTQ-Orbitrap proves reliability and reveals complementary ionization preferences. Mol Cell Proteomic, 12(10), 2911-2920. PMID: 23788530

Percy, A.J.; Chambers, A.G.; Yang, J.; et al. 2013. Method and platform standardization in MRM-based quantitative plasma proteomics. J Proteomics, 95, 66-76. PMID: 23933160

Chambers, A.G.; Percy, A.J.; Yang, J.; et al. 2013. Multiplexed quantitation of endogenous proteins in dried blood spots by multiple reaction monitoring-mass spectrometry. Mol Cell Proteomics, 12(3), 781-791. PMID: 23221968 

Butko, M.T.; Savas, J.N.; Friedman, B.; et al. 2013. In vivo quantitative proteomics of somatosensory cortical synapses shows which protein levels are modulated by sensory deprivation. Proc Natl Acad Sci, USA, 110(8), E726-E735. PMID: 23382246

Hebert, A.S.; Merrill, A.E.; Bailey, D.J.; Still, A.J.; Westphall, M.S.; Strieter, E.R.; Pagliarini, D.J.; Coon, J.J. 2013. Neutron-encoded mass signatures for multiplexed proteome quantification. Nat Methods, 10(4), 332-334. PMID: 23435260

Rauniyar, N.; McClatchy, D.B.; Yates, J.R. III. 2013. Stable isotope labeling of mammals (SILAM) for in vivo quantitative proteomic analysis. Methods, 61(3), 260-268. PMID: 23523555

Rayavarapu, S.; Coley, W.; Cakir, E.; et al. 2013. Identification of disease specific pathways using in vivo SILAC proteomics in dystrophin deficient mdx mouse. Mol Cell Proteomics. 12(5). 1061-1073. PMID: 23297347

Simon, G.M.; Cheng, J.; Gordon, J.I. 2012. Quantitative assessment of the impact of the gut microbiota on lysine ε-acetylation of host proteins using gnotobiotic mice. Proc Natl Acad Sci USA, 109, 11133-11138. PMID: 22733758

Dey, A.; Seshasayee, D.; Noubade, R.; et al. 2012. Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation. Science, 337(6101), 1541-1546. PMID: 22878500

Sharma, N.; Medikayala, S.; Defour, A.; et al. 2012. Use of quantitative membrane proteomics identifies a novel role of mitochondria in healing injured muscles. J Biol Chem, 287(36), 30455-30467. PMID: 22778268

Savas, J.N.; Toyama, B.H.; Xu, T.; et al. 2012. Extremely long-lived nuclear pore proteins in the rat brain. Science, 335(6071), 942. PMID: 22300851

Price, J.C.; Khambatta, C.F.; Li, K.W.; et al. 2012. The Effect of Long Term Calorie Restriction on in Vivo Hepatic Proteostatis: A Novel Combination of Dynamic and Quantitative Proteomics. Mol Cell Proteomics, 11(12), 1801-1814. PMID: 22984287

Stergachis, A.; MacLean, B.; Lee, K.; et al. 2011. Rapid empirical discovery of optimal peptides for targeted proteomics. Nat Methods, 8(12), 1041-1043. PMID: 22056677

Hoofnagle A. 2010. Peptide Lost and Found: Internal Standards and the Mass Spectrometric Quantification of Peptides. Clin Chem, 56(10), 1515-1517. PMID: 20739635

Park, S.K.; Venable, J.D.; Xu, T.; et al. 2008. A quantitative analysis software tool for mass spectrometry-based proteomics. Nat Methods, 5(4), 319-322. PMID: 18345006

McClatchy, D.B.; Yates, J.R. III. 2008. Stable Isotope Labeling of Mammals (SILAM). CSH Protoc, doi:10.1101/pdb.prot 4940. PMID: 21356771

Goshima, N.; Kawamura, Y.; Fukumoto, A.; et al. 2008. Human protein factory for converting the transcriptome into an in vitro-expressed proteome. Nat Methods, 5(12), 1011-1017. PMID: 19054851

McClatchy, D.B.; Dong, M.Q.; Wu, C.C.; et al. 2007. ¹⁵N metabolic labeling of mammalian tissue with slow protein turnover. J. Proteome Res, 6(5), 2005-2010. PMID: 17375949

Mann, M. 2006. Functional and quantitative proteomics using SILAC. Nat Rev Mol Cell Biol, 7(12), 952-958. PMID: 17139335

Amanchy, R.; Kalume. D.E.; Pandey, A. 2005. Stable isotope labeling with amino acids in cell culture (SILAC) for studying dynamics of protein abundance and posttranslational modifications. Sci STKE, 267, 1-20. PMID: 15657263

Shadforth, I.P., et al. 2005. i-Tracker: for quantitative proteomics using iTRAQ^®. BMC Genomics, 6, 145. PMID: 16242023

MacCoss, M.J., et al. 2005. Measurement of the isotope enrichment of stable isotope-labeled proteins using high-resolution mass spectra of peptides. Anal Chem, 77(23), 7646-7653. PMID: 16316172

Kratchmarova, I.; Blagoev. B.; Haack-Sorensen. M.; et al. 2005. Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation. Science, 308(5727), 1472-1477. PMID: 15933201

Sadygov, R.; Cociorva, D.; Yates, J.R., III. 2004. Large-scale database searching using tandem mass spectra: looking up the answer in the back of the book. Nat Methods, 1(13), 195-202. PMID: 15789030

Blagoev, B.; Ong, S.E.; Kratchmarova. I.; et al. 2004. Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nature Biotechnol, 22(9), 1139-1145. PMID: 15314609

Wu, C.C.; MacCoss, M.J.; Howell, K.E.; et al. 2004. Metabolic labeling of mammalian organisms with stable isotopes for quantitative proteomic analysis. Anal Chem, 76(17), 4951-4959. PMID: 15373428

Ficarro, S.B., et al. 2002. Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol, 20(3), 301-305. PMID: 11875433

Ong, S.E.; Blagoev, B.; Kratchmarova, I.; et al. 2002. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics, 1(5), 376-386. PMID: 12118079

Goshe, M.B.; Conrads, T.P.; Panisko, E.A.; et al. 2001. Phosphoprotein isotope-coded affinity tag (PhIAT) approach for isolating and quantitating phosphopeptides in proteome-wide analyses. Anal Chem, 73(11), 2578-2586. PMID: 11403303

Conrads, T.P.; Alving, K.; Veenstra, T.D.; et al. 2001. Quantitative analysis of bacterial and mammalian proteomes using a combination of cysteine affinity tags and ¹⁵N-metabolic labeling. Anal Chem, 73(9), 2132–2139. PMID: 11354501

Washburn, M.P.; Wolters, D.; Yates, J.R., III. 2001. Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat Biotechnol, 19(3), 242-247. PMID: 11231557

Pasa-Tolic, L.; Jensen, P.K.; Anderson, G.A.; et al. 1999. High throughput proteome-wide measurements of protein expression using mass spectrometry. J Am Chem Soc, 121(34), 7949-7950. JACS DOI:10.1021/ja991063o

Oda, Y.; Huang, K.; Cross, F.R.; et al. 1999. Accurate quantitation of protein expression and site-specific phosphorylation. Proc Natl Acad Sci USA, 96(12), 6591-6596. PMID: 10359756

Gygi, S.P.; Rist, B.; Gerber, S.A.; et al. 1999. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat Biotechnol, 17(10), 994-999. PMID: 10504701

Barlos, K.; Gatos. D. 1999. 9-Fluorenylmethyloxycarbonyl/tButyl-based convergent protein synthesis. Biopolymers, 51(4), 266-278. PMID: 10618595

Fujiwara, Y.; Akaji, K.; Kiso, Y. 1994. Racemization-Free Synthesis of C-Terminal Cysteine-Peptide Using 2-Chlorotrityl Resin. Chem Pharm Bull, 42(3), 724-726. PMID: 8004723

Barlos, K.; Gatos, D.; Kallitsis, J.; et al. 1989. Synthesis of Protected Peptide-Fragments Using Substituted Triphenylmethyl Resins. Tetrahedron Lett, 30, 3943-3946.

McNurlan, M.A.; Pain, V.M.; Garlick, P.J. 1980. Conditions that alter rates of tissue protein synthesis in vivo. Biochem Soc Trans, 8(3), 283-285. PMID: 6772491

NMR Solvents and Consumables

Miscellaneous
 

Metals

Hsu, W.H.; Jiang, S.J.; Sahayam, A.C. 2013. Determination of Cu, As, Hg and Pb in vegetable oils by elctrothermal vaporization inductively coupled plasma mass spectrometry with palladium nanoparticles as modifier. Talanta, 117, 268-272. PMID: 24209340

Busto, ME.; Montes-Bayon, M.; Sanz-Medel, A. 2006. Accurate determination of human serum transferrin isoforms: Exploring metal-specific isotope dilution analysis as a quantitative proteomic tool. Analytical Chemistry, 78(24), 8218-8226. PMID: 17165810

Chang, C.W.; Fennimore, A.M.; Afanasiev, A.; et al. 2006. Isotope efect on the thermal conductivity of boron nitride nanoubes. Phys Rev Lett, 97(8), 085901. PMID: 17026316

Encinar, J.R.; Villar, M.I.; Santamaria, V.G.; et al. 2001. Simultaneous determination of mono-, di-, and tributyltin in sediments by isotope dilution analysis using gas chromatography-ICPM. Anal Chem, 73(13), 3174-3180. PMID: 11467570

Matlock, M.M.; Howerton, B.S.; Atwood, D.A. 2001. Irreversible precipitation of mercury and lead. J Hazard Mater, 84(1), 73-82. PMID: 11376885

Compounds

Xu, J.; Zhu, P.; Gan, Z.; et al. 2010. Natural-abundance 43Ca solid-state NMR spectroscopy of bone. J Am Chem Soc, 132(33), 11504-11509. PMID: 20681578

Miwa, K.; Takano, J.; Fujiwara, T. 2006. Improvement of seed yields under boron-limiting conditions through overexpression of BOR1, a boron transporter for xylem loading, in Arabidopsis thaliana. Plant J, 46(6), 1084-1091. PMID: 16805739

Takano, J.; Miwa, K.; Yuan, L.; et al. 2005. Endocytosis and degradation of BOR1, a boron transporter of Arabidopsis thaliana, regulated by boron availability. Proc Natl Acad Sci U S A, 102(34),12276-12281. PMID: 16103374

Lee, K.H.; Liu, S.H.; Jiang, S.J. 1998. Determination of cadmium and lead in urine by electrothermal vaporization isotope dilution inductively coupled plasma mass spectrometry. Analyst,123(7), 1557-1560. PMID: 9830167

¹³C Breath Test Substrates 

Song M.; Camargo M.C.; Weinstein S.J.; et al. 2018. Serum pepsinogen 1 and anti-Helicobacter pylori IgG antibodies as predictors of gastric cancer risk in Finnish males. Aliment Pharmacol Ther, 47(4), 494-503. PMID: 29243850

Hwang Y.-J.; Kim N.; Lee H.S.; et al. 2018. Reversibility of atrophic gastritis and intestinal metaplasia after Helicobacter and pylorieradication - a prospective study for up to 10 years. Aliment Pharmacol Ther, 47(3), 380-390. PMID: 29193217

Venerito M.; Schneider C.; Costanzo R.; et al. 2018. Contribution of Helicobacter pylori infection to the risk of peptic ulcer bleeding in patients on nonsteroidal anti-inflammatory drugs, antiplatelet agents, anticoagulants, corticosteroids and selective serotonin reuptake inhibitors. Aliment Pharmacol Ther, 47(11), 1464-1471. PMID: 29655196

Gatta L.; Scarpignato C.; Fiorini G.; et al. 2018. Impact of primary antibiotic resistance on the effectiveness of sequential therapy for Helicobacter pylori infection: lessons from a 5-year study on a large number of strains. Aliment Pharmacol Ther, 47(9), 1261-1269. PMID: 29536561

Zamani M.; Ebrahimtabar F.; Zamani V.; et al. 2018. Systematic review with meta-analysis: the worldwide pevalence of Helicobacter pylori infection. Aliment Pharmacol Ther, 47(7), 868-876. PMID: 29430669

Hu Y.; Wan J.-H.; Li X.-Y.; et al. 2017. Systematic review with meta-analysis: the global recurrence rate of Helicobacter pylori. Aliment Pharmacol Ther, 46(9), 773-779. PMID: 28892184

Kwon, Y.; Jeon S.; Nam S.; et al. 2017. Helicobacter pylori infection and serum level of pepsinogen are associated with the risk of metachronous gastric neoplasm after endoscopic resection. Aliment Pharmacol Ther, 49(8), 758-767. PMID: 28799258

Zagari R.M.; Rabitti S.; Greenwood D.C.; et al. 2017. Systematic review with meta-analysis: diagnostic performance of the combination of pepsinogen, gastrin-17 and anti-Helicobacter pylori antibodies serum assays for the diagnosis of atrophic gastritis. Aliment Pharmacol Ther, 46(7), 657-667. PIMD: 28782119

Modak, A. 2017. Point-of-care companion diagnostic tests for personalizing psychiatric medications: Fulfilling an unmet clinical need. J Breath Res, 12(1), 01701. PMID: 28920579

Pan, W.; Wang, Z.; Tian, F.; et al. 2017. Electroacupuncture combined with mosapride alleviates symptoms in diabetic patients with gastroparesis. Exp Ther Med, 12(4), 1637-1643. PMID: 28413522

Gorowska-Kowolik, K.; Chobot, A.; Kwiecien, J. 2017. ¹³C Methacetin Breath Test for Assessment for Microsomal Liver Function: Methodology and Clinical Application. Gastroenterol Res Pract, 2017, 7397840. PMID: 28757868

Franken, J.; Mauritz, F.A.; Stellato, R.K.; et. al. 2017. The Effect of Gastrostomy Placement on Gastric Function in Children: a Prospective Cohort Study. J Gastrointest Surg, 21(7), 1105-1111. PMID: 28424983

Moran, S.; Duque, X.; Xochiquetzal Ortiz-Olvera, N.; et al. 2017. Utility of ¹³C-methacetin breath test in predicting long-term survival of patients with decompensated cirrhosis. J Breath Res, 11(3), 036011. PMID: 28649974

Caviglia, G.P.; Sguazzini, C.; Cisaro, F.; et al. 2017 . Gastric emptying and related symptoms in patients treated with buspirone, amitriptyline or clebopride: a "real world" study by ¹³C-octanoic acid breath test. Minerva Med, 108(6), 489-495. PMID: 28707862

Rubin, T.; Heyne, K.; Luchterhand, A.; et al. 2017. Kinetic validation of the LiMAx test during 10,000 intravenous ¹³C-methacetin breath tests. J. Breath Res, 12(1), 016005. PMID: 28742055

Moran, S.; Mina, A.; Duque, X.; et al. 2017. The utility of the ¹³C-methacetin breath test in predicting the long-term survival of patients with decompensated cirrhosis. J Breath Res, 11(3), 036011. PMID: 28649974

Matsumoto H.; Shiotani A.; Katsumata, R.; et al. 2016. Helicobacter pylori eradication with proton pump inhibitors or potassium-competitive acid blockers: the effect of clarithromycin resistance. Dig Dis Sci, 61 (11), 3215-3220. PMID: 27659671

Maldonado-Hernandez, J.; et al. 2016. The ¹³C-glucose breath test for insulin resistance assessment in adolescents: comparison with fasting and post-glucose stimulus surrogate markers of insulin resistance. J Clin Res Pediatr Endocrinolog, 8(4), 419-424. PMID: 27354200

Modak, A.S.; Klyarytska, I.; Kriviy, V.; et al. 2016. The effect of proton pump inhibitors on the CYP2C19 enzyme activity evaluated by the pantoprazole-¹³C breath test in GERD patients: clinical relevance for personalized medicine. J Breath Res, 10(4), 046017. PMID: 27991432

Harvey, A.; Modak, A.; Dery, U.; et al. 2016. Changes in CYP2C19 enzyme activity evaluated by the [(13)C]-pantoprazole breath test after co-administration of clopidogrel and proton pump inhibitors following percutaneous coronary intervention and correlation to platelet reactivity. J Breath Res, 10(1), 017104. PMID: 26815196

Furnari, M.; Ahmed, I.; Erpecum, K.J.; et. al. 2016. Breath Tests in Assess Alcoholic Liver Disease. Rev Recent Clin Trials, 11(3), 185-190. PMID: 27515960

Kempinski, R.; Neubaur, K.; Wieczorek, S.; et. al. 2016. ¹³C-Methacetin Breath Testing in Patients with Non-Alcoholic Fatty Liver Disease. Adv Clin Exp Med, 25(1), 77-81. PMID: 26935501

Jara, M.; Bednarsch, J.; Malinowski, M.; et. al. 2016. Effects of oxaliplatin-based chemotherapy on liver function--an analysis of impact and functional recovery using the LiMAx test. Langenbecks Arch Surg, 401(1), 33-41. PMID: 26507639

Siddiqui, I.; Ahmed, S.; Abid, S. 2016. Update on diagnostic value of breath test in gastrointestinal and liver diseases. World J Gastrointest Pathophysiol, 7(3), 256-265. PMID: 27574563.

Chapman, M.J.; Deane, A.M.; O'Connor, S.L.; et al. 2016. The effect of camicinal (GSK962040), a motilin agonist, on gastric emptying and glucose absorption in feed-intolerant critically ill patients: a randomized, blinded, placebo-controlled, clinical trial. Crit Care, 20(1), 232. PMID: 27476581

Usai-Satta, P.; Oppia, F.; Scarpa, M.; et al. 2016. Delayed gastric emptying does not normalize after gluten withdrawal in adult celiac disease. Scand J Gastroenterol, 51(8), 923-926. PMID: 27161492

Hauser, B.; Roelants, M.; De Schepper, J.; et al. 2016. Gastric emptying of solids in children: reference values for the (13) C-octanoic. Neurogastroenterol Motil, 28(10), 1480-1487. PMID: 27098977

Horner, K.M.; Finlayson, G.; Byrne, N.M.; et al. 2016. Food reward in active compared to inactive men: Roles for gastric emptying and body fat. Physiol Behav, 160, 43-49. PMID: 27072508
Maldonado-Hernandez, J et al. 2016. The ¹³C-Glucose Breath Test for Insulin Resistance Assessment in Adolescents: Comparision with Fasting and Post-Glucose Stimulus Surrogate Markers of Insulin Resistance. J Clin Res Prediatr Endocrinol, 8(4), 419-424. PMID: 27354200

Tack, J.; Rotondo, A.; Meulemans, A.; et al. 2016. Randomized clinical trial: a controlled pilot trial of the 5-HT4 receptor agonist revexepride in patients with symptoms suggestive of gastroparesis. Neurogastroenterol Motil, 28(4), 487-497. PMID: 27010235

Hellstrom, P.M.; Tack, J.; Johnson, L.V.; et al. 2016. The pharmacodynamics, safety and pharmacokinetics of single doses of the motilin agonist, camicinal, in type 1 diabetes mellitus with slow gastric emptying. Br J Pharmacol, 173(11), 1768-1777. PMID: 26924243.

Thazhath, S.S.; Wu, T.; Bound, M.J.; et al. 2016. Administration of resveratrol for 5 wk has no effect on glucagon-like peptide 1 secretion, gastric emptying, or glycemic control in type 2 diabetes: a randomized controlled trial. Am J Clin Nutr, 103(1), 66-70. PMID: 26607942.

Opdam, F.L.; Modak, A.S.; Gelderblom, H.; et al. 2015. Further characterization of a 13C-dextromethorphan breath test for CYP2D6 phenotyping in breast cancer patients on tamoxifen therapy. J Breath Res, 9(2), 026003. PMID:25891764

Opdam, F.L.; Modak, A.S.; Mooijaart, S.P.; et al. 2015. CYP2D6 Metabolism in Frail Elderly Compared to Non-Frail Elderly: A Pilot Feasibility Study. Drugs & Aging. 32(12), 1019-1027. PMID: 26597400

Safgren, S.L.; Suman, V.J.; Kosel, M.L.; et al. 2015. Evaluation of CYP2D6 enzyme activity using a 13C-dextromethorphan breath test in women receiving adjuvant tamoxifen. Pharmacogenet Genomics, 25(4), 157-163. PMID: 25714002

Stravitz, R.T.; Reuben, A.; Mizrahi, M.; et. al. 2015. Use of the methacetin breath test to classify the risk of cirrhotic complications and mortality in patients evaluated/listed for liver transplantation. J Hepatol, 63(6), 1345-1351. PMID: 26220750.

Jara, M.; Bednarsch, J.; Valle, E.; et al. 2015. Reliable assessment of liver function using LiMAx. J Surg Res, 193(1), 184-189. PMID: 25150081

Meyer, R.; Foong, R.X.; Thapar, N.; et al. 2015. Systematic review of the impact of feed protein type and degree of hydrolysis on gastric emptying in children. BMC Gastroenterol, 15, 137. PMID: 26472544    

Epprecht, L.; Schreglmann, S.R.; Goetze, O.; et. al. 2015. Unchanged gastric emptying and visceral perception in early Parkinson's disease after a high caloric test meal. J Neurol, 262(8), 1946-1953. PMID: 26048686. 

Horner, K.M.; Byrne, N.M.; Cleghorn, G.J.; et al. 2015. Influence of habitual physical activity on gastric emptying in healthy males and relationships with body composition and energy expenditure. Br J Nutr, 114(3), 489-496 PMID: 26168984.

Gourcerol, G.; Tissier, F.; Melchior, C.; et al. 2015. Impaired fasting pyloric compliance in gastroparesis and the therapeutic response to pyloric dilatation. Aliment Pharmacol Ther, 41(4), 360-367. PMID: 25523288

Bonfrate, L.; Grattagliano, I.; Palasciano, G.; et al. 2015. Dynamic carbon 13 breath tests for the study of liver function and gastric emptying. Gastroenterol Rep, 3(1), 12-21. PMID: 25339354

Grattagliano, I.; Bonfrate, L.; Lorusso, M.; et al. 2015. Exploring liver mitochondrial function by 13C-stable isotope breath tests: implications in clinical biochemistry. Methods Mol Biol, 1241, 137-152. PMID: 25308494.

Hijaz, N.M.; Friesen, C.A.; Schuman, J.V.; et al. 2015. Plasma ghrelin and liquid gastric emptying in children with functional dyspepsia consistent with post-prandial distress syndrome. Neurogastroenterol Motil, 27(8), 1120-1126. PMID: 25962328.

Hersch, M.; Krasilnikov, V.; Helviz, Y.; et al. 2015. Prokinetic drugs for gastric emptying in critically ill ventilated patients: Analysis through breath testing. J Crit Care, 30(3), 655.e7-13. PMID: 25746849.

Klieber, M.; Oberacher, H.; Hofstaetter, S. et al. 2015. Phenoconversion by Routinely Prescribed Proton Pump Inhibitors Omeprazole and Esomeprazole: Clinical Implications for Personalized Medicine.Journal of Pharmacology and Experimental Therapeutics.  354 (3) 426-430. ASPET

Inoue, S.; Sakamoto, Y.; Sekino, Y. et al. 2015. Low-dose ramosetron accelerates gastric emptying in the early phase: A crossover study in healthy volunteers using a continuous real-time 13C breath test (BreathID System) Turk J Gastroenterol.  26:123-7. PMID: 25835109  

Hussain M. et al. 2014. [13C]Glucose Breath Testing Provides a Noninvasive Measure of Insulin Resistance: Calibration Analyses Against Clamp Studies. Diabetes Technology & Therapeutics.16. 2. NCBI

Konstantinou, D.; Margariti, K; Hadziyannis, E.; et al. 2014. Significance of the 13C-caffeine breath test for patients with cirrhosis. Annals of Gastroenterology 27,53-59. NCBI.

Adhikari, J.; Fitzgerald, M.C. 2014  SILAC-Pulse Proteolysis: A Mass Spectrometry-Based Method for Discovery and Cross-Validation in Proteome-Wide Studies of Ligand Binding. J Am Soc Mass Spectrom, 25(12), 2073-2083. PMID: 25315461

Fierbinteanu-Braticevici, C.; Papacocea, R.; Tribus, L.; et al 2014. Role of 13C methacetin breath test for non invasive staging of liver fibrosis in patients with chronic hepatitis C. Indian J Med Res, 140(1), 123-129. PMID: 25222787.

Thazhath, S.S.; Wu, T.; Bound, M.J.; et al. 2014. Changes in meal composition and duration affect postprandial endothelial function in healthy humans. Am J Physiol Gastrointest Liver Physiol, 307(12), G1191-G1197. PMID: 25342049 

Horner, K.M.; Byrne, N.M.; Cleghorn, G.J.; et. al. 2014. Reproducibility of gastric emptying in overweight and obese males. Clin Nutr, 33(4), 684-688. PMID: 24074547

Kawamura, M.; Nakada, K.; Konishi, H.; et al. 2014. Assessment of motor function of the remnant stomach by 13C breath test with special reference to gastric local resection. World J Surg, 38(11), 2898-28903. PMID: 24934641.

Kasicka-Jonderko, A.; Jonderko, K.; Gajek, E.; et al. 2014. Sluggish gallbladder emptying and gastrointestinal transit after intake of common alcoholic beverages. J Physiol Pharmacol, 65(1), 55-66. PMID: 24622830.

Clegg, M.E.; Shafat, A. 2014. The effect of agar jelly on energy expenditure, appetite, gastric emptying and glycaemic response. Eur J Nutr, 53(2), 533-539. PMID: 23872837.

Maldonado-Hernandez, J.; Prina-Ojeda., L.; Montalvo-Velarde. et al. 2014 . Validity and reliability of the 13C-methionine breath test for the detection of moderate hyperhomocysteinemia in Mexican adults. 52(5). PMID: 24607920

Modak, A.S. 2013. Regulatory issues on breath tests and updates of recent advances on [13C]-breath tests. J Breath Res, 7(3), 037103. PMID: 23774086 

Opdam, F.L.; Modak, A.S.; Gelderblom, H. et al. 2013. Breath tests to phenotype drug disposition in oncology. Clin Pharmacokinet, 52(11), 919-926. PMID: 23868281  

Opdam, F.L.; Dezentje, V.O.; den Hartigh, J.; et al. 2013. The use of the 13C-dextromethorphan breath test for phenotyping CYP2D6 in breast cancer patients using tamoxifen: association with CYP2D6 genotype and serum endoxifen levels. Cancer Chemother Pharmacol, 71(3), 593-601. PMID: 23228987

Thacker, D.L.; Modak, A.; Flockhart, D.A.; et al. 2013. Is (+)-[13C]-pantoprazole better than (±)-[13C]-pantoprazole for the breath test to evaluate CYP2C19 enzyme activity? J Breath Res, 7(1), 016001. PMID: 23257668

Cunha-Junior, G.F.; De Marco, L.; Bastos-Rodrigues, L.; et. al. 2013. (13)C-uracil breath test to predict 5-fluorouracil toxicity in gastrointestinal cancer patients. Cancer Chemother Pharmacol, 72(6), 1273-1282. PMID: 24101147.

Fierbinteanu-Braticevici, C.; Plesca, D.A.; Tribus, L.; et al. 2013. The role of 13C-methacetin breath test for the non-invasive evaluation of nonalcoholic fatty liver disease. J Gastrointestin Liver Dis, 22(2), 149-156. PMID: 23799213.

Holzhutter, H.G.; Lock, J.F.; Taheri, P.; et. al. 2013. Assessment of hepatic detoxification activity: proposal of an improved variant of the (13)C-methacetin breath test. PLoS One, 8(8), e70780. PMID: 23967104.

Kochel-Jankowska, A.; Hartleb, M.; Jonderko, K.; et. al. 2013. 13C-methacetin breath test correlates with clinical indices of liver disease severity in patients with primary biliary cirrhosis. J Physiol Pharmacol, 64(1), 27-33. PMID: 23568968

Vranova, J.; Hendrichova, M.; Kolarova, H.; et al. 2013. 13C-methacetin breath test in the evaluation of disease severity in patients with liver cirrhosis. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 157(4), 392-400. PMID: 23549507   

Kasicka-Jonderko, A.; Jonderko, K.; Budniok, M.; et al. 2013. Comparison of two dosage regimens of the substrate for the [13C]methacetin breat test. Isotopes Environ Health Stud, 49(1), 109-121. PMID: 22827182

Shteyer, E.; Lalazar, G.; Hemed, N.; et. al. 2013. Continuous 13C-methacetin breath test differentiates biliary atresia from other causes of neonatal cholestasis. J Pediatr Gastroenterol Nutr, 56(1), 60-65. PMID: 22695040

Bruno, G.; Lopetuso, L.R.; Laniro, G.; et al. 2013. 13C-octanoic acid breath test to study gastric emptying time. Eur Rev Med Pharmacol Sci, 17, 59-64. PMID: 24443070

Salles Junior, L.D.; Santos, P.R.; dos Santos, A.A.; et al. 2013. Dyspepsia and gastric emptying in end-stage renal disease patients on hemodialysis. BMC Nephrol, 14, 275. PMID: 24330675

Gourcerol, G.; Benanni, Y.; Boueyre, R.; et al. 2013. Influence of gastric emptying on gastro-esophageal reflux: a combined pH-impedance study. Neurogastroenterol Motil, 25(10), 800-e634. PMID: 23848571

Lorenz, M.; Pfeiffer, C.; Steinstrasser, A.; et al. 2013. Effects of lixisenatide once daily on gastric emptying in type 2 diabetes-relationship to postprandial glycemia. Regul Pept, 185, 1-8. PMID: 23665027

Nguyen, N.Q.; Bryant, L.K.; Burgstad, C.M.; et al. 2013. Gastric emptying measurement of liquid nutrients using the (13)C-octanoate breath test in critically ill patients: a comparison with scintigraphy. Intensive Care Med, 39(7), 1238-1246. PMID: 23471513.

Dickman, R.; Zilper, T.; Steinmetz, A.; et al. 2013. Comparison of continuous breath test and gastric scintigraphy for the measurement of gastric emptying rate in healthy and dyspeptic individuals. Eur J Gastroenterol Hepatol, 25(3), 291-295. PMID: 23354159

Clegg, M.E.; Ranawana, V.; Shafat, A.; et al. 2013. Soups increase satiety through delayed gastric emptying yet increased glycaemic response. Eur J Clin Nutr, 67(1), 8-11. PMID: 23093339.

Modak, A.; Durso, R.; Josephs, E.; Rosen, D. 2012. A rapid non invasive L-DOPA-¹³C breath test for optimally suppressing extracerebral AADC enzyme activity - toward individualizing carbidopa therapy in Parkinson’s disease. J Parkinsons Dis, 2(4), 349-356. PMID: 23646099

Modak, A.S. 2012. Phenotype Breath Tests as Companion Diagnostic Tests (CDx) in Clinical Trials of Drugs. J Pharmacogenomics Pharmacoproteomics. 3(1), (2pp). http://www.omicsonline.org

Higashida, M.; Matsumoto, H.; Kubota, H.; et. al. 2012. Evaluation of 5-FU plasma concentration by 13C breath test in patients treated with oral 5-FU analogs. Anticancer Res, 32(12), 5407-5414. PMID: 23225444

Ishii, Y.; Suzuki, S.; Asai, S.; et al. 2012. Liver function assessment with three (13)C breath tests by two-point measurements. Isotopes Environ Health Stud, 48(4), 543-557. PMID: 22540278

Nobrega, A.C.; Ferreira, B.R.; Oliveira, G.J.; et al. 2012. Dyspeptic symptoms and delayed gastric emptying of solids in patients with inactive Crohn's disease. BMC Gastroenterol, 12, 175. PMID: 23216812

Doi, H.; Sakakibara, R.; Sato, M.; et al. 2012. Plasma levodopa peak delay and impaired gastric emptying in Parkinson's disease. J Neurol Sci, 319(1-2), 86-88. PMID: 22632782.

Hoffman, I.; Tack, J. 2012. Assessment of gastric motor function in childhood functional dyspepsia and obesity. Neurogastroenterol Motil, 24(2), 108-112. PMID: 22103293

Modak, A.S. 2011. Barriers to overcome for transition of breath tests from research to routine clinical practice. J Breath Res, 5(3), 030202. PMID: 21900729 

Thacker, D.L.; Modak, A.; Nguyen, P.D.; et al. 2011. Stereoselective pharmacokinetics of stable isotope (+/-)-[13C]-pantoprazole: Implications for a rapid screening phenotype test of CYP2C19 activity. Chirality, 23(10), 904-909. PMID: 21935988

Kasicka-Jonderko, A.; Nita, A.; Jonderko, K.; et al. 2011. C-methacetin breath test reproductivity study reveals persistent CyP1A2. World J Gastroenterol, 17(45), 4979-4986. PMID: 22174547.

Razlan, H.; Marzuki, N.M.; Tai, M.L.; et al. 2011. Diagnostic value of the C methacetin breath test in various stages of chronic liver disease. Gastroenterol Res Pract, 2011, 235796. PMID: 21687605.

Kasicka-Jonderko, A.; Loska, D.; Jonderko, K.; et al. 2011. Interference of acute cigarette smoking with [13C]methacetin breath test. Isotopes Environ Health Stud, 47(1), 34-41. PMID: 21287423.

Ron, Y.; Sperber, A.D.; Levine, A.; et. al. 2011. Early satiety is the only patient-reported symptom associated with delayed gastric emptying, as assessed by breath-test. J Neurogastroenterol Motil, 17(1), 61-66. PMID: 21369493

Hope, H.B.; Medhus, A.W.; Sandstad, O.; et al. 2011. Reduced 13C-D-xylose absorption in alcoholics is more likely caused by alterations in small intestinal mucosa than delayed gastric emptying. Scand J Gastroenterol, 46(4), 414-419. PMID: 21275757

Janssen, P.; Van Oudenhove, L.; Casteels, C.; et al. 2011. The effects of acute citalopram dosing on gastric motor function and nutrient tolerance in healthy volunteers. Aliment Pharmacol Ther, 33(3), 395-402. PMID: 21118281. 

Bluck, L.J.; Jackson, S.J.; Vlasakakis, G.; et al. 2011. Bayesian hierarchical methods to interpret the (13)C-octanoic acid breath test for gastric emptying. Digestion, 83(1-2), 96-107. PMID: 21042021

Dickman, R.; Steinmetz, A.; Bernnstine, H.; et al. 2011. A novel continuous breath test verus scintigraphy for gastric emptying rate measurement. J Clin Gastroenterol, 45(1), 22-25. PMID: 20495467. 

Ranawana, V.; Clegg, M.E.; Shafat, A; et al. 2011. Postmastication digestion factors influence glycemic variability in humans. Nutr Res, 31(6), 452-459. PMID: 21745627.

Banasch, M.; Ellrichmann, M.; Tannapfel, A. et al. 2011. The Non-Invasive 13C-Methionine Breath Test Detects Hepatic Mitochondrial Dysfunction As a Marker of Disease Activity In Non-Alcoholic Steatohepatitis. Eur J Med Res. 258-264. PMID: PMC3353401

Modak, A.S. 2010. Breath biomarkers for personalized medicine. Personalized Medicine, 7(6), 640-651. Future Medicine

Modak, A.S. 2010. Single time point diagnostic breath tests: a review. J Breath Res, 4(1), 017002. PMID: 21386204 

Ishii, Y.; Suzuki, S.; Takahashi, Y.; et al. 2010. Can the 2-(13)C-uracil breath test be used to predict the effect of the antitumor drug S-1? Cancer Chemother Pharmacol, 66(2), 333-343. PMID: 19921195

Azulay, D.O.; Stunder, D.; Wilson, F. 2010. Stochastic simulations of the exponential-beta function as an assessment of the validity of the choice of the Wagner-Nelson method for the analysis of 13C-octanoic acid breath tests. J Breath Res, 4(3), 036001. PMID: 21383478 

Sfarti, C.; Trifan, A.; Hutanasu, C.; et al. 2010. Prevalence of gastroparesis in type 1 diabetes mellitus and its relationship to dyspeptic symptoms. J Gastrointestin Liver Dis,19(3), 279-284. PMID: 20922192.

Grattagliano, I.; Lauterburg, B.H.; Palasciano, G.; et al. 2010. 13C-breath tests for clinical investigation of liver mitochondrial function. Eur J Clin Invest, 40(9), 843-850. PMID: 20597965

Clegg, M.E.; Shafat, A. 2010. Procedures in the 13C Octanoic breath test for measurement of gastric emptying: analysis using Bland-Altman methods. Scand J Gastroenterol, 45(7-8), 852-861. PMID: 20443742.

Perri, F.; Bellini, M.; Portincasa, P.; et al. 2010. (13)C-octanoic acid breath test (OBT) with a new test meal (EXPIROGer): Toward standardization for testing gastric emptying of solids. Dig Liver Dis, 42(8), 549-553. PMID: 20116352.

Duro, D.; Fitzgibbons, S.; Valim, C. et al. 2010. [13C]Methionine Breath Test to Assess Intestinal Failure-Associated Liver Disease. Pediatr Res. 68(4)-349-354. PMID: 20581744

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Modak, A.S. 2007. Stable isotope breath tests in clinical medicine: a review. J Breath Res, 1(1), 014003. PMID: 21383429

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Modak, A.S. 2006. Racial Differences in Dihydropyrimidine Dehydrogenase Activity: Increased Prevalence of DPD Deficiency in African Americans Compared to Caucasians. Clin Cancer Res, 12, 5491-5495.

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