Application Notes

Proteomics | Metabolic Research | Biomolecular NMR | Standards for Environmental Analysis

	Proteomics
	QC and Quantitation Kits
	Translation and Implementation of PeptiQuant™ Plus Human Plasma BAK-270	Application Note 50
	Metabolic Labeling
	Metabolic Isotopic Analysis Reveals Mitochondrial Loss of Function in pRb-Deficient Cells in vivo	Application Note 45
	Analysis of Tyrosine Kinase Signaling in Human Cancer by Stable Isotope Labeling with Heavy Amino Acids in Mouse Xenografts Utilizing Mouse Express^® Lysine ¹³C₆ Mouse Feed	Application Note 32
	Targeted LC-SRM/MS Quantification of Mammalian Synaptic Proteins with Mouse Express^® Brain Tissue, a New Isotopically Labeled Proteome Standard	Application Note 27
	Stable Isotope Labeling in Mammals with ¹⁵N Spirulina	Application Note 24
	Metabolic Incorporation of Stable Isotope Labels into Glycans	Application Note 23
	Stable Isotope Labeling in Proteomics	Application Note 11
	Chemical Tagging
	Individuality Normalization when Labeling with Isotopic Glycan Hydrazide Tags (INLIGHT™)	Application Note 37
	The Use of Adenosine 5'-Triphosphate for the Unambiguous Identification of Phosphopeptides	Application Note 17
	Specific Isotopic Labeling of Methyl Groups Has Extended the Molecular Weight Limits for NMR Studies of Protein Structure and Dynamics	Application Note 16
	Protein Expression
	Full-Length Expressed Stable Isotope-Labeled Proteins for Quantification	Application Note 40
	Stable Isotope Dimethyl Labeling	Application Note 38
	Metabolism
	Analysis of Whole-Body Branched-Chain Amino Acid Metabolism in Mice Utilizing 20% Leucine ¹³C₆ and 20% Valine ¹³C₅ Mouse Feed	Application Note 43
	Fluxing Through Cancer: Tracking the Fate of ¹³C-Labeled Energy Sources Glucose and Glutamine in Cancer Cells and Mouse Tumors	Application Note 34
	*Tracing Lipid Disposition in vivo* Using Stable Isotope-Labeled Fatty Acids and Mass Spectrometry**	Application Note 31
	*Determination of Nitric Oxide Production and de novo* Arginine Production with Stable Isotopes**	Application Note 30
	Determining Protein Turnover in Fish with D₇-Leucine	Application Note 29
	Metabolomics
	From QC to Quantitation: Utility of QReSS™ Metabolites in FBS Measurements	Application Note 51
	S tandardizing Quantitative Metabolomics Analyses Through the QReSS™ Kit	Application Note 49
	Organic Acid Quantitation in Mouse Muscle by Ion Chromatography-Mass Spectrometry with Isotopically Labeled Standards	Application Note 47
	Thermo-CIL App Note Pathway Targeted Metabolomic Analysis in Oral-Head and Neck Cancer Cells Using IC-MS	Application Note 44



	Biomolecular NMR
	In situ Protein Expression
	Cell-Free Protein Synthesis with ²H/¹⁵N/¹³C-Labeled Amino Acids in H₂O for the Production of Perdeuterated Proteins with 1H in the Exchangeable Positions	Application Note 36
	In vivo Protein Expression
	Isotope Labeling of Alanine Methyl Groups on a Deuterated Background for NMR Studies of High-Molecular-Weight Proteins	Application Note 25
	[2,3-¹³C]-Labeled Aromatic Residues as a Means to Improving Signal Intensities and Kick-Starting the Assignment of Membrane Proteins by Solid-State MAS-NMR	Application Note 22
	Effective Site Specific Isotopic Labeling ¹⁵N, ¹³C Glycine; ¹⁵N, ¹³C Phenylalanine; ¹⁵N Tryptophan) Expression Optimization Using BioExpress® 2000 Media	Application Note 20
	in vitro Protein Synthesis of Perdeuterated Proteins for NMR Studies	Application Note 19
	Top Ten Tips for Producing ¹³C, ¹⁵N Protein in Abundance	Application Note 15
	Efficient Uniform Isotope Labeling of Proteins Expressed in Baculovirus-Infected Insect Cells Using BioExpress^® 2000	Application Note 14
	Optimization of BioExpress Supplementation of M9 Cultures	Application Note 12
	Membrane Proteins
	Uniform Isotope Labeling of Eukaryotic Proteins in Methylotrophic Yeast for High-Resolution NMR Studies – Extension to Membrane Proteins	Application Note 26
	Selective Labeling
	Production of U-[²H], Thyr-γ2[¹³CH₃] Labeled Proteins for Methyl-TROSY NMR	Application Note 39
	Hyperpolarization/MRI/MRS
	Development of Hyperpolarized Metabolic Contrast Agents Using PASADENA	Application Note 21
	Methyl and Amino Acid Type Labeling
	Stereospecific Leu/Val Methyl Labeling: An Important Technology for NMR Studies of High-Molecular-Weight Complexes	Application Note 48


	Standards for Environmental Analysis
	Ecotoxicology and Exposure Analysis
	Human Biomonitoring: Attogram Level Sensitivity and Consequences for Analytical Standards Purity	Application Note 35

	Other Misc.
	Using Stable Isotopes to Solve Problems in Combinatorial Chemistry	Application Note 10

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