As of June 12, 2018 our Privacy Policy has been updated. For individuals in the European Union, CIL uses cookies on this website. Please review the new privacy statement to see how. By continuing to use this website you agree to us using cookies in accordance with our privacy statement. Click here for the new privacy statement..OK

Corporate Overview

IsoTopics™ – November 2022

TurnoveR: A Skyline External Tool for Analysis of Protein Turnover in Metabolic Labeling Studies

Basisty, N.; Shulman, N.; Wehrfritz, C.; et al.

Protein turnover dynamics is often investigated to better understand biological processes and its impact on health and disease. This is accomplished through the analysis of stable isotope metabolic labeling data. Although several computational tools exist, bioinformatics remains a challenge. To help overcome this bottleneck (in context of MS proteomics data), Schilling et al. developed a novel algorithm – TurnoveR  for the automated evaluation of protein turnover in Skyline software. The guidelines and features of TurnoveR are demonstrated in this article using two different mouse metabolic labeling studies.

Read article


Stable Isotope Newsletters | Cambridge Isotope Laboratories
stable isotope, stable isotope labeled compounds, environmental contaminant standards
CIL has been ready to help with the analytical standards critical to the task of defining and resolving any major environmental contamination problems.