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IsoTopics™ – May 2018

A Timeline of Stable Isotopes and Mass Spectrometry in the Life Sciences

Lehmann, W.
Here Wolf-Dieter Lehmann chronicles the development of stable isotopes (principally 13C, D, 15N, and 18O) and the MS-based techniques used for their analysis. The review is divided into time segments (1920-1950, 1950-1980, 1980-2000, and 2000-2010), with methods and applications discussed therein.  Included in the highlights is the use of stable isotopes (as quantitative standards or metabolic tracers) with LC- or GC-MS to address questions in ‘omics (e.g., metabolomics, proteomics, and lipidomics), metabolism, and forensics, among other fields of application.
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Stable Isotope Newsletters | Cambridge Isotope Laboratories
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