Cambridge Isotope Laboratories, Inc. (CIL) is proud to offer an assortment of deuterated phospholipids and detergents manufactured by FB Reagents, Ltd. These compounds are being used to solubilize isotopically labeled membrane proteins for high-field nuclear magnetic resonance (NMR) spectroscopy, and to study membrane structure by small-angle neutron scattering (SANS). FBR’s products significantly expand CIL’s current offering of deuterated lipids and detergents.

 

“We are excited to work with CIL to make our compounds accessible to more researchers worldwide,” says Dr. Vlado Gelev, President and Founder of FB Reagents. “Cambridge Isotopes is the most recognizable name in stable isotopes, and one of the oldest companies in the business. We have a lot to learn from them.” 

 

“As these products aid NMR investigations into membrane protein structure and dynamics, they will be an exciting and useful addition to our BioNMR product portfolio,” says Dr. Kevin Millis, CIL Senior Scientist. Kevin continues, “These are special molecules because the deuteration boosts the NMR signal and minimizes overlap in NMR spectra, provides contrast in SANS data, and extra selectivity in mass spectral data. Hence, they can be used in a variety of ways.”  Vlado adds, “A surprising benefit of deuteration is that the higher cost of the samples makes an already discerning customer even more critical, while it also justifies extra attention by our chemist (e.g., multiple purification steps). As a result these lipids and detergents are often of higher purity than their natural abundance analogs.”


 

About Cambridge Isotope Laboratories, Inc.

CIL is the world’s largest manufacturer and global supplier of stable isotopes and stable isotope-labeled compounds used in research, environmental, neonatal, pharmaceutical, medical diagnostic, OLED, and industrial markets. CIL is an operating business owned by Otsuka Pharmaceuticals. The CIL business consists of two facilities in the Boston, MA, area; a large isotope-enrichment production plant in Xenia, OH; CIL China; CIL Canada; ABX in Dresden, Germany; and Eurisotop in Saclay, France. For more information on CIL, visit isotope.com. 

 


About FB Reagents

Founded in Cambridge, MA, in 2008 and currently located in Bulgaria, FB Reagents (fbreagents.com) is one of the first and most trusted suppliers of deuterated phospholipids and detergents. The company has been supplying membrane mimics for NMR research since 2008, starting with the first NMR structure determination of an integral membrane protein.