CIL Isotope Separations (CIS) – Xenia, OH USA

CIS is the world leader in the separation of ¹³C and ¹⁸O. CIL separates both ¹³C and ¹⁸O at its Xenia, Ohio, facility and has the world’s largest production capacity for both ¹³C and ¹⁸O. CIL also has the only large-capacity nongovernmental D₂O (deuterium oxide) enrichment columns in the world located at its CIS facility. 

Carbon-13 Isotope Separation Facility
CIL is recognized as the world leader in the separation of ¹³C. In the 1980s, CIL took the initiative to construct the world’s largest ¹³C isotope-separation plant in order to provide a sufficient supply of ¹³C starting materials to support new research and diagnostic developments. CIL recently embarked on a significant expansion of its ¹³C production capacity and maintains its leadership position in the separation of ¹³C. 

Oxygen-18 Isotope Separation Facility
In 2000, CIL responded to the worldwide shortage of ¹⁸O water by embarking on the construction of the world’s largest ¹⁸O isotope-separation facility. Responding to the increasing needs of the nuclear medicine community, CIL has increased production capacity of ¹⁸O multiple times since 2000. With each expansion, CIL has maintained its position as the world’s leading producer of ¹⁸O. CIL’s ¹⁸O water is used in positron emission tomography (PET) and energy-expenditure studies.