Deuterated NMR Solvents

Yes. Often solvent users require a specific custom mixture of two or more solvents. CIL’s expert packaging technicians are uniquely qualified to formulate custom solvent preparations

Dimethyl Sulfoxide (DMSO) has a melting point of 18^oC, freezing close to room temperature. Sometimes when it is delivered it will be in a solid state. To return the material to a liquid state, thaw it in a warm water bath.  Care must be taken to prevent water contamination.

If you have more than ~16 L you may require multiple carboys, please just ask. 

CIL recommends the refrigeration of solvents packaged in septum bottles to extend the product shelf life, high purity and ensure product quality.  Septum bottles should be tested after 6 months.

To measure acidity in deuterium oxide solutions: calculate pD by adding 0.4 to the reading taken from the glass electrode pH meter (Glasoe andLong, J. Phys. Chem., 64, 188 (1960)).

In order to avoid isotopic contamination, some products, especially deuterated compounds, should be handled under an inert atmosphere, such as dry nitrogen or argon.

CIL also specializes in ¹³C-depleted and deuterium-depleted compounds. Please contact us if you do not see the ¹³C depleted/deuterium depleted compound of interest.

We recommend that chloroform, diethyl ether, diglyme, tetrahydrofuran, and TMS be stored in the refrigerator.

The NMR Solvent Data Chart is available as a laminated reference document.  Please contact your Customer Account Coordinator to request a copy.

No! Fill the bulk carboy container ~80% full. Most are shipped by FedEx Air, and if full, the carboy is likely to expand and possibly rupture the container.

DLM-45, Sodium deuteroxide (D, 99.5 %),

Molarity Calculation from Weight Percentage

DLM-45 has a concentration of 40 % NaOD in D₂O, by weight (w/w).  This means 40 g NaOD per 100 g of solution.  The D₂O accounts for the remaining 60 g of the solution.  

What is the molarity of this solution?  Molarity (M) is defined as the number moles of solute, per liter (L) of solution. 

𝑀𝑜𝑙𝑎𝑟𝑖𝑡𝑦 ,𝑀.= ,𝑚𝑜𝑙𝑒𝑠 𝑜𝑓 𝑠𝑜𝑙𝑢𝑡𝑒-𝑙𝑖𝑡𝑒𝑟𝑠 𝑜𝑓 𝑠𝑜𝑙𝑢𝑡𝑖𝑜𝑛.

Taking 40 g of solute (NaOD) and its molecular weight (MW = 41.01 g/mol),  we divide mass by MW to get 0.9754 mols for 40 g NaOD.

40 𝑔 𝑁𝑎𝑂𝐷 × ,1 𝑚𝑜𝑙 𝑁𝑎𝑂𝐷-41.01 𝑔 𝑁𝑎𝑂𝐷.=0.9754 𝑚𝑜𝑙𝑠 𝑁𝑎𝑂𝐷

We need the density of deuterium oxide, D₂O, to find what volume 60 g will occupy.  The density is 1.103 g/mL, so 1L D₂O will weigh 1,103 g.  We get the volume of D₂O in L, by dividing the mass, 60 g D₂O, by the mass of one liter, to get 0.0544 L D₂O. 

60 𝑔 ,𝐷-2.𝑂 ×,1 𝐿 ,𝐷-2.𝑂-1,103 𝑔 ,𝐷-2.𝑂 .=0.0544 𝐿 ,𝐷-2.𝑂

Assuming the NaOD occupies no additional volume in the solution,  the volume of D₂O is equal to the volume of the solution.  Dividing 0.9754 mols NaOD by 0.0544 L gives 17.93 moles NaOD per L, about 18 M.

,0.9754 𝑚𝑜𝑙𝑠 𝑁𝑎𝑂𝐷-0.0544 𝐿.=17.93 ,𝑚𝑜𝑙𝑠-𝑙𝑖𝑡𝑒𝑟. ≈18 𝑀

We have assumed that slight variations of MW due to isotopic enrichment, and density variations with temperature can be ignored.  

Yes, CIL has a D₂O recovery program.

Some of the benefits of participation in this program include a credit to your CIL account.

To learn more about this program, please contact your customer service representative at 1-800-322-1174 (North America) or 1-978-749-8000 (International)