|CIL offers the most complete listing of metabolic substrates available. Some of the many applications for these materials include the utilization of amino acids for protein/amino acid turnover studies, carbohydrates for glucose metabolism studies, and fatty acids for lipolysis research. Stable isotope labeling of these materials allows investigators to study metabolic pathways in living systems in a manner which is safe and non-invasive.
CIL recognizes the importance of high chemical purity and isotopic enrichment for metabolic studies and tests all products to meet
high specifications for both. All products are shipped with a Certificate of Analysis that indicates the passing results and an MSDS to describe the physical characteristics and safety of the product. CIL may be able to provide additional data upon request. CIL can also offer products that are microbiological tested. An Enhanced Technical Data Package (EDP) is available for some microbiological tested products (MPT).
CIL is able to manufacture compounds to current Good Manufacturing Practice (cGMP). A majority of isotope-labeled compounds can be manufactured compliant with ICH Q7A “cGMP Guidance for Active Pharmaceutical Ingredients (APIs).” Most products can be tested to USP and/or EP specifications. Our Clinical Trial Material (CTM) product line is suitable for use in early phase clinical trials. Material suitable for Phase II and Phase III Clinical Trials can also be provided. Please contact your local sales representative for more information.
Click here to download our Research Use Statement. Click here to download CIL's Product Quality Designations. Click here to download CIL's Enhanced Technical Data Package (EDP).
CIL research products are labeled "For Research Use Only. Not for use in diagnostic procedures." CIL -CTM grade products are labeled "For Investigational Use Only. The performance characteristics of this product have not been established."