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The Standard December 2010

CIL Continues Development of Toxaphene Congener Standards:

Commercial Toxaphene, known by a variety of trade names, is a technical mixture of several hundred chlorinated Camphenes. It is an extremely effective pesticide, and was used extensively when DDT was banned from use. However, because of the complexity of the technical mixture analysis has been difficult, and the dearth of pure, high-quality individual standards has hindered development of robust analytical methods. Until recently, no 13C-Toxaphene congeners were available, preventing analysts from enjoying the benefits of Isotope Dilution Mass Spectrometry (IDMS).

After finding initial success replacing DDT in many agricultural applications, within a few years Toxaphene too was banned for most uses in much of the world. In 2001 Toxaphene, was included in the first round of chemical pollutants covered by the Stockholm Treaty; one of the “Dirty Dozen.” For more information on Toxaphene and the Stockholm convention, click here: Stockholm Convention “Dirty Dozen” POPs.

As with the analysis of other complex mixtures such as PCBs (Aroclors; Kanechlors) and BDEs (commercial PentaBDEs and OctaBDEs), most analysts have focused on methods that target key congeners. In PCB analyses, most laboratories target the WHO “Dioxin-Like” PCBs and/or the Predominant or “Marker” congeners. Since toxicity data is still being developed for BDEs, BDE analysis tends towards those Predominant congeners found in relatively high levels in the technical products. While Toxaphene analysis is still waiting for a definitive method, researchers tend to focus on the most bioaccumulative congeners such as Parlar 26, 50, and 62.

With that in mind, CIL completed the arduous synthesis of uniformly ¹³C-labeled Camphene, which was then selectively chlorinated, and target congeners were isolated. Unlabeled standards have been produced under the rigorous Certified Standard protocols developed by CIL for unlabeled PCB and BDE standards, and these were used to certify the ¹³C-labeled analogues. Currently, CIL offers 7 unlabeled and 7 ¹³C-Labeled individual congeners, and is producing more as customer demand warrants.

CLM-7930-1.2 Parlar 26 (¹³C₁₀)
ULM-7828-1.2 Parlar 26 (unlabeled)

CLM-8705-1.2 Parlar 32 (¹³C₁₀)
ULM-8665-1.2 Parlar 32 (unlabeled)

CLM-8719-1.2 Parlar 39 (¹³C₁₀)
ULM-8767-1.2 Parlar 39 (unlabeled)

CLM-7931-1.2 Parlar 50 (¹³C₁₀)
ULM-7829-1.2 Parlar 50 (unlabeled)

CLM-7932-1.2 Parlar 62 (¹³C₁₀)
ULM-7830-1.2 Parlar 62 (unlabeled)

CLM-8720-1.2 Parlar 69 (¹³C₁₀)
ULM-8768-1.2 Parlar 69 (unlabeled)

CLM-8721-1.2 Parlar 70 (¹³C₁₀)
ULM-8769-1.2 Parlar 70 (unlabeled)

Terry Grim
Environmental Sales Manager
Ph: 978-296-1932
Ph: 800-322-1174 x1932
Mobile: 978-884-1688
terryg@isotope.com

Ben Priest
Environmental Account Manager
Ph: 978-296-1931
Ph: 800-322-1174 x1931
Mobile: 978-973-0971
benp@isotope.com

Jay Grazio
Environmental Account Coordinator
Ph: 978-296-1933
Ph: 800-322-1174 x1933
isotope.com
jayg@isotope.com

New Products:
Oil Dispersant "DOSS"
Cod Liver Oil CRM
PPCPs in Polar Solvent
POPs Pesticides Mixtures
Perfluorinated Compounds
PCBs
Flame Retardants

Featured Products:
Bisphenol-A (ring-¹³C₁₂)
US EPA 16 PAH Cocktail (¹³C)

Articles:

CIL Continues Development of Toxaphene Congener Standards:

CIL's 2010 Environmental Contaminant Standards Catalog is now available!

EPA takes action on Chemicals used in Dyes, Flame Retardants, and Industrial Detergents

New 13C-Labeled Standard for Chemical Dispersant Used in Gulf Oil Spill:

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Andover, MA
01810-5413 USA
PH: 978.749.8000
PH: 800.322.1174
FAX:978.749.2768

All prices are in U.S. dollars for North American customers. All international customers should contact their local independent sales representatives or CIL International sales.